PM414. The impact of long acting paliperidone palmitate on clinical outcomes and hospital stay in routine clinical practice: a UK service evaluation
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چکیده
منابع مشابه
Long-acting paliperidone palmitate – interim results of an observational study of its effect on hospitalization
Paliperidone palmitate (PP) is a recently introduced long-acting atypical, or second-generation, antipsychotic. Published data on PP are currently limited to controlled trials and case reports. In this observational study, we followed up 200 consecutive patients prescribed PP in normal practice. After 1 year, 65% of patients were still receiving PP. The number of admissions to hospital in the y...
متن کاملIs paliperidone palmitate more effective than other long-acting injectable antipsychotics?
BACKGROUND Paliperidone palmitate is one of the most widely prescribed long-acting injectable (LAI) antipsychotics in the UK. However, it is relatively expensive and there are few data comparing its effectiveness to that of other LAI antipsychotics. We sought to address this issue by analyzing a large anonymized electronic health record (EHR) dataset from patients treated with LAI antipsychotic...
متن کاملComparative effectiveness of long-acting antipsychotics: issues and challenges from a pragmatic randomised study.
Although long-acting antipsychotics are widely used in individuals with psychotic disorders, it is unclear which long-acting preparation should be considered as first-line treatment in clinical practice. In this commentary, the main strengths and weaknesses of a recently published pragmatic randomised study comparing long-acting paliperidone palmitate v. long-acting haloperidol decanoate are br...
متن کاملManagement of antipsychotic treatment discontinuation and interruptions using model-based simulations
BACKGROUND Medication nonadherence is a well described and prevalent clinical occurrence in schizophrenia. These pharmacokinetic model-based simulations analyze predicted antipsychotic plasma concentrations in nonadherence and treatment interruption scenarios and with treatment reinitiation. METHODS Starting from steady state, pharmacokinetic model-based simulations of active moiety plasma co...
متن کاملModeling the budget impact of long-acting injectable paliperidone palmitate in the treatment of schizophrenia in Japan
BACKGROUND The cost of schizophrenia in Japan is high and new long-acting injectable (LAI) antipsychotics might be able to reduce costs by causing a reduction of hospital stays. We aim to estimate budget effects of the introduction of a new 1-month LAI, paliperidone palmitate, in Japan. METHODS A budget impact analysis was conducted from a payer perspective. The model took direct costs of ill...
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عنوان ژورنال:
دوره 19 شماره
صفحات -
تاریخ انتشار 2016